Signature Medical Group is a physician-owned, multi-specialty physician group comprised of more than 75 doctors. We provide care from 22 locations primarily covering the greater St. Louis area. The organization was formed in 2001 when physicians at Mid County Orthopaedic Surgery & Sports Medicine and Premier Care Orthopedics joined to form the largest orthopedic physician group in the St. Louis area. Our practice has grown and presently includes some of the area’s most highly respected physicians specializing in orthopedics, obstetrics, gynecology, gastroenterology, maternal-fetal medicine, gynecologic oncology, allergy and immunology. Now one of the largest physician groups in Missouri, Signature Medical Group is leading the way to better health.